In 2009, Winfrey's Harpo Productions and Sony Pictures launched a syndicated daily talk show featuring Oz, called The Dr. Oz Show.

Oz was born in Cleveland, Ohio, to Turkish parents Suna and Mustafa, who had immigrated from Konya, Turkey. Mustafa was born in Bozkır, a small town in central Turkey. Mustafa did very well in school and earned scholarships that allowed him to emigrate to the United States as a medical resident in 1955. Suna comes from a wealthy family that includes writers, civil engineers, and businessmen. Several of her great-grandparents came from the Caucasus mountains, leaving the region after the Russian Empire took it over in the 1860s.

Mehmet Oz was educated at Tower Hill School in Wilmington, Delaware. In 1982 he received his undergraduate degree from Harvard University. In 1986, he obtained a joint MD and MBA degree from the University of Pennsylvania School of Medicine and The Wharton School. He was awarded the Captain’s Athletic Award for leadership in college and was Class President followed by President of the Student Body during medical school.

Oz is Vice-Chair and Professor of Surgery at Columbia University. He directs the Cardiovascular Institute and Complementary Medicine Program at New York-Presbyterian Hospital. His research interests include heart replacement surgery, minimally invasive cardiac surgery, and health care policy. He has authored over 400 original publications, book chapters, and medical books and has received several patents. He performs around 250 heart operations annually.

Oz is the founder and chairman of HealthCorps, a non-profit organization that pays a small stipend to recent college graduates to spend two years in high schools mentoring students about health, nutrition, and fitness.

Oz appeared as a health expert on The Oprah Winfrey Show for five seasons. His Transplant! television series won both a Freddie and a Silver Telly award. He has appeared on Good Morning America, the Today show, Larry King Live and The View, as well as guest-hosting the Charlie Rose show. In addition, he served as medical director of Denzel Washington’s John Q and participated in several other feature films. He currently hosts The Dr. Oz Show on television and a talk show on Sirius XM Radio.

Oz authored six New York Times best sellers including You: The Owner’s Manual, You: The Smart Patient, YOU: On a Diet, YOU: Staying Young, YOU: Being Beautiful as well as the award winning Healing from the Heart. His new book, YOU: Having a Baby, was published by Free Press on December 1, 2009. He has a regular column in Esquire magazine and O, The Oprah Magazine and his article “Retool, Reboot, and Rebuild” was awarded the 2009 National Magazine Award for Personal Service.

Time magazine ranked Oz 44th on its list of the 100 Most Influential People in 2008 and Esquire magazine placed him on its list of the 75 Most Influential People of the 21st Century. He was called a Global Leader of Tomorrow by the World Economic Forum and one of “The Harvard 100 Most Influential Alumni” by 02138 magazine. He won the Gross Surgical Research Scholarship. He was listed in “Doctors of the Year” by Hippocrates magazine and in “Healers of the Millennium” by Healthy Living magazine. Oz is annually listed in the Castle Connolly Guide of the top United States doctors, as well as other ranking groups.[citation needed]

Other awards and honors include:

Oz lives in northern New Jersey with his wife Lisa. They have been married since 1985 and have four children: Daphne, Arabella, Zoe, and Oliver.